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Abstract #2477

Comparison Study of Intensity Non Uniformity Correction Methods for 3DT1 MRI Acquisitions

Nicolas Vibet1, 2, Franois De Guio, 23, Aurlien Monnet4, Nadine Girard5, Stphane Lehricy, 26, Sophie Prusat7, Carole Dufouil8, Christine Delmaire, 24, Cyril Poupon, 29, Marie Chupin1, 2

1CRICM, UPMC URMR_S975, INSERM U975, CNRS UMR7225, ICM, Paris, France; 2CATI, multicentre neuroimaging platform, Paris, France; 3LNAO, Neurospin, CEA, Gif-sur-Yvette, France; 4Department of Neuroradiology, APHP, Lille, France; 5Department of Neuroradiology, Hopital Timone, Marseille, France; 6CRICM & CENIR, UPMC/CNRS/INSERM/ICM, Paris, France; 7U593, INSERM, Bordeaux, France; 8U897, INSERM, Bordeaux, France; 9LRMN, Neurospin, CEA, Gif-sur-Yvette, France

Intensity non-uniformity is often largely visible in 3DT1 acquistions; it can lead to difficulties in advanced data analysis. Several methods are available, from manufacturers or post processing tools, but their use in multicentre study has yet to be evaluated; we compared the performances of manufacturers intensity non uniformity correction tools with two available post processing methods (BrainVISA and SPM) for three scanners (Siemens 1,5T and 3T, Philips 3T). This analysis is based on four quality indices computed on the image and its itensity histogram. In the framework of multicentre analyses, post-processing methods appear to be better adapted and perform satisfactorily.

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Keywords

accurate acquisitions advanced advantages aimed allow analyses apart appear appeared approaches artifact automatic available better bias boundary brain characteristics checked chosen clinicians collected combinations combining complementary compulsory computed computing considered continuous contrast coronal corrected correction corrections correctly datasets decrease decreased derived detect determined differ displayed done drawbacks either ellipsoid embedded entropy environment evaluate evaluation example explained extensible faced field finally freely fully global gray histogram homogeneous include index indicates influence info inherent inhomogeneity initiative intensity involving jack lien location major manually manufacturer manufacturers many mask measures mechanisms memento merge mode modes named native nevertheless often overall pair pathological peak pilot placed post potentially preliminary probability processing project projects protocols quality reduce reduced reducing rely repeat reported restored review reviews scanner scanners segmentation segmentations sequentially sharing sharper software softwares stage steps strategies structural studies subject subjects suffer sufficient tend tissue together tools understand undertaken unified uniformity valley variation visualize visually white whole