Meeting Banner
Abstract #2401

Whole-Prostate T2 Mapping in Under 6 Minutes Using Autocalibration and Partial-Fourier MRI

Harsh Kumar Agarwal1, Julien Sngas2, Baris Turkbey3, Marcelino Bernardo3, Tim Nielsen2, Jochen Keupp2, Peter L. Choyke3

1Philips Research NA, Briarcliff Manor, NY, United States; 2Philips Research Europe, Hamburg, Germany; 3National Institute of Health, Molecular Imaging Program, National Cancer Institute, Bethesda, MD, United States

T2-weighted MRI has successfully been used in diagnostic prostate MRI. However, a clinically feasible T2 mapping technique is essential to develop a quantitative MR imaging framework for prostate oncology. This work proposes a novel image acquisition and image reconstruction protocol which exploit the temporal redundancy in the multi-echo fast spin echo imaging sequence used for T2 mapping along with coil sensitivity profile and partial-Fourier MRI to generate T2 maps over whole prostate on the scanner in clinically feasible time of 5min and 55 seconds.

Keywords

accelerated acceleration according account accountability accuracy achieved acquisition amount anterior approved around array artifact artifacts axial best board calibration cancer cardiac central channel characteristics clinical clinically coil coils combination combined comes commonly compliant compute consent consists cover critically cross dataset decreases depicting described determined develop diagnostic direct dynamic ease echoes element encoding error essential estimating estimator even exam example exploiting exploits fast feasible fold framework fully generate half hamburg harsh health identify improving institute institutional insurance interleaved likelihood linear local longer majority manor mapping maps marked matrix minutes missing molecular national negative neighboring noise novel oncology parallel parametric partial patient patients phantom portability previously process profiles proposed proposes prostate protocol quantitative reconstruction rectal reduce reduction redundancy resolution respectively review sampled sampling scanned scanner section sense sensitivity signs slice slices sonar space spatial specificity spin step structures successfully support surface table talk temporal theory tissue together tumor typical various vial vials whole