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Abstract #2317

Effect of Trajectory Delay in Cine Ultra-Short TE Phase-Contrast MR Imaging of the Carotid Bifurcation

Mo Kadbi1, Hui Wang1, Lizette Warner2, Melanie Traughber2, Motaz Alshaher1, Andrea Yancey3, Jens Heidenreich1, Amir A. Amini1

1University of Louisville, Louisville, KY, United States; 2Philips healthcare, Cleveland, OH, United States; 3VA hospital, Louisville, KY, United States

UTE phase contrast may be a more accurate technique for measurment of blood flow with higher Reynolds numbers. Additional potential application areas for UTE PC MRI is measurement of blood flow in the presence of atherosclerotic disease where there is turbulent and disturbed flow distal to a stenosis. UTE can remedy intravoxel dephasing which leads to signal loss and reduce errors in velocity measurment . These delays can result in phase errors that may affect the accuracy and reliability of flow measurements. In this work we present a UTE-PC sequence to measure the disturbed blood flows and show that correction of these phase errors improves the result of UTE-PC technique dramatically. Here, the proposed sequence is utilized to quantitatively measure blood velocity in the carotid bifurcation which is associated with disturbed blood flow and results are compared to standard PC MRI sequences.

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Keywords

accuracy accurate acquisitions additional affect aortic application applied approaches arch artery artifact artifacts auto axial bifurcation blood bottom calculation calculations calibration calibrations capability capable careful carotid centric changing channel characterized cine circle clear coil column combined comparable compensated consecutive contrast corrected correction correlation delay delays disease distal disturbed done dramatically eddy element enable encoding errors evaluated examined field flow flows gradient gradients graph help hospital improves in vivo incorrect inhomogeneity internal investigated lead leads loss magnitude measure measured minimizing moment must negligible original oversampling peak phantom phys physical potential presence previously prior profile proposed pulse quantitatively radial readout readouts reduce reduced related reliability remedy resolution respectively revealing scanner scanning sense sensitive short slice slightly space spatial subsequent subsequently subtracted suffers switching systole third trajectories trajectory turbulent typically ultra utilized valve velocity vessels volunteer warner years