What Is the Best Way to Use Hyperoxia to Measure Venous Cerebral Blood Volume?

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accounts achieved additional allowed almost alone analogy arterial arteries assumes best blood bold brain broaden broadens capillaries caused causes cerebral challenge challenges changing combinations compartments component concentration considering contrast contribution contributions controlled correction creating decrease defined density dependent detailed determination dominated elements enables enabling error estimating examined exhibits experiment explained extraction firstly fits fitting fixed fraction fractions generated gives grows hence ideal important includes independent introduced know knowing leading likely located makes many measure measured measuring model much multiplying normalization normalized numerically original outcomes oxygen paired paradoxical partial percentage perhaps physiological plotted plotting presence prevent produce produced proportional propose proposed quantity random reduced reduces reduction regardless relationship represents require respectively respiratory response resting sample saturation scatter secondly selected sensitivity significantly simple simulated source studies subjects substantial suggests systematic tight tighter tightly tissue transport true typically uncertainty uncontrolled underlying unknown unlike variability variables variations varied vascular vein veins venous vessel volume yields