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Abstract #2146

Investigating the Duration of Brain Response to Acupuncture Stimulation by Using Independent Component Analysis

Tomokazu Murase1, Masahiro Umeda2, Yuko Kawai2, Yasuharu Watanabe2, Toshihiro Higuchi, Chuzo Tanaka

1Department of Neurosurgery, Meiji University of integrative Medicine, Nantan-shi, Kyoto, Japan; 2Department of informatics, Meiji University of integrative Medicine

We examined the correlation between the selected ICs and some hypothetical GLMs and predicted the temporal delay in brain activation induced by acupuncture. The fMRI data were analyzed using Tensor-ICA, and IC-related cerebral activity with each stimulation was selected to the activation area by referring to previous studies. Acupuncture stimulation for a duration of 15 s resulted in little cerebral activity; however, a duration of 30 s resulted in great cerebral activity in the predictable area. In conclusion, we found that changes in BOLD signals caused by acupuncture stimulation lasted for around 15 s after the stimulation.

Keywords

activation activity acupuncture analyzed anterior approximately around axial bidirectional bilateral block blocks bold brain brushing caused cerebral certain coefficient coefficients coil component components computed consensus consisted control convolving correlation cortex cortices course cross definite delay derived design designs difficult duration electric evaluated even event every examined expected final findings frequency function functional general great hand head healthy highest hypothetical included independent induced induction informatics integrative interpretation interspersed investigating involves japan lasted linear little manual many materials matrix median medicine melodic model models motion needle negative nerve neurosurgery onset pain palm paradigm part participants persist predictable predicted previous processed reached real received recent referring regressors related remaining reported response responses rest rotation runs sample scale schematic score selected several sham skin slices sponge stimulation stimulations studies subjects summarized system table tactical tactile tapping task temporal tensor thirteen types typically uncorrected underwent useful various version women years