Meeting Banner
Abstract #2049

Direct SENSE Imaging for Fast, Multi-Echo FMRI Over a Restricted Field of View

Mark Chiew1, 2, Simon J. Graham1, 3

1Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; 2Rotman Research Institute, Toronto, Ontario, Canada; 3Imaging Research, Sunnybrook Research Institute, Toronto, Ontario, Canada

We present a novel method for fast acquisition of densely-sampled multi-echo fMRI data over a restricted field of view. The DSI (Direct SENSE Imaging) technique employs a modified STEAM localization method for selective excitation of a small number of voxels, and uses direct sensitivity encoding for spatial separation of measured signals. The readout requires no imaging gradients as no Fourier encoding is performed, and the received signals contain both T2 and T2* contrast. This method is proposed as a promising alternative to whole-brain approaches for fast imaging in targeted, ROI-based fMRI.

Keywords

absence acceleration accommodate achievable achieve achieved acquiring acquisition acquisitions amplitudes applications apply approximately array assumption available ball band bandwidth better bold brain called capable channel coil coils collecting combining comparing complex comprised constant constrains contrast cuboid decay define densely developed dictates direct directly distinct easily encoding entirely exactly excitation excite fact fast field form free full fully general generated gradient gradients graham greatly implementation independent induction initially inserted inside institute inverse inversion investigations kept lack least linear localization locations long matrix medical modified modulation much multiplying often overall parallel particular phantom placed placement practice procedures profiles prototype pulse pulses readout receive reconstructed reconstruction reduce reduced reducing reduction removing represent required requiring resolution restricted robustness rows sampled sampling savings schematic selected selective sense sensitivity separation shaded shimming significantly simulations skipping soccer spatial spectral spectroscopy spins spoiler spurious steam steps strategically suppression system take taken targeted temporal trans typically user varied view whole