Meeting Banner
Abstract #2008

Improved Selection of the Venous Blood Pool for OEF Determination: IQ-OEF

Sophie Schmid1, Esben T. Petersen2, Jeroen Hendrikse2, Andrew Webb1, Matthias J.P. van Osch1, 3

1C.J. Gorter Center for High Field MRI, Dept. of Radiology, Leiden University Medical Center, Leiden, Netherlands; 2Dept. Radiology and Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands; 3Leiden Institute of Brain and Cognition, Leiden, Netherlands

A new method called Inflow QUIXOTIC (IQ) is introduced, which employs a pulsed ALS module at T1blood*ln(2) seconds before VS-labeling to null the arterial pool. By nulling the arterial signal, the venous pool will be labeled exclusively by a single VS-module. IQ with and without QUIPSS was compared to QUIXOTIC. IQ enables selection of the local venous blood pool, showed a higher SNR, and provides also the opportunity to not only estimate the venous, but also the arterial T2. Whereas T2 measurements in large vessels (both arteries and veins) were feasible with our current sequence, tissue measurements were hampered by artifacts.

Abstract PDF Poster PDF

Keywords

acquisition acts addition advantage affairs allows applied arterial arteries artery artifacts attributed blood bold brain causing cerebral challenging channel circulation cognition coil combination combinations concept consumption contaminations control delay deposition dept developed diastole direct distinguished division downside dutch economic efficiency either enables encoding evaluating exclusion exclusively exponential extra extraction feasible field fitted five flow flowing foundation fresh function furthermore great greater head healthy important improvement inclusion inflow institute introduced inverted isolate label labeled labeling larger latter local localized locally mask medical metabolic ministry module modules mono moreover null nulling occlusion opportunity optimized oxygen paired pairwise partial pathologies pathology perfusion plot pool protocol pulse pulsed quantifies quantitative quixotic radiology radiotherapy read receive related remain require saturate saturation scanned scanner scheme selection selective selectively side significantly since sinus slice spin spins star statistical stroke subtraction suffers suppress systole technology thresholded tissue trade triggered types ultimately unit useful veins velocity venous vessels volunteer volunteers