Automatic Extraction of an AIF Using a Novel Blood-Tissue Equilibrium Approach

Keywords

absolute accurately acquisition addition agent allows animals apparent approximation arterial artery assume assumed assumes assumption automated automatic automatically better black blood blue calibration capillaries caudal clearly coded commonly comparable compartment concentration condition contrast convoluted corrected correspond corresponds coupled curve curves decay depend described describing determine determined developed distribution distributions dosed dots dynamic equation equilibrium example except exchange existence expected experimental exploits exponential expressed extracellular extract extraction filtered final fits fitted function gadolinium identically inductively inflammation initial injected injection input inside inspection instead invasive kinetic known limited located manual maps martin mass minutes model noisy novel overlapping peak perceived perhaps physiologic plasma population predicted preparation prepared presence proper proposed pseudo quickly rats reached real represent representative residuals resolution reveals sampled sampling scanner selected served several shape significantly simple spatial spectrometry spectrum steady substituting suggesting superimpose superimposed superimposes superimpositions tail temporal theory thirty tissue tissues trans user usually variation vary varying volume yielding