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Abstract #1944

A Simple Isotropic Phantom for Diffusional Kurtosis Imaging

Els Fieremans1, Antonio Pires1, Jens H. Jensen1

1CBI, Radiology, New York University School of Medicine, New York, NY, United States

Heat-treated heavy dairy cream is shown to have a diffusion coefficient and a diffusional kurtosis similar to values for in vivo brain and may therefore serve as a practical and inexpensive phantom for testing diffusional kurtosis imaging (DKI) protocols intended for neuroimaging applications. A feature of the phantom is that the fat/water shift may be exploited to provide a nontrivial consistency check. This phantom may be particularly useful as a calibration reference for multicenter and longitudinal investigations.

Keywords

addition additional adjust agreement aliquots allowed allowing anisotropy apparent applications assuming attention bath bias brain calibration cancer channel check clearly clinical coefficient coil comp compartment compensating consistency convenient cool coronal cream dairy decay derived described deviations diffusion diffusional diffusivity directly disorder displacement distribution drawn enables encoding errors establish evaluate evaluating exchanging exploited feature fitted fitting fraction fractional frequency function give good head heat heating heavy house human hyperactivity illustrated in vivo increasing indicate inexpensive intended investigating isotropic known kurtosis longitudinal magma maps material measured measures medicine metrics mild minimal minimize minutes modeled molecules neglecting noise nonzero parallel parametric phantom phantoms plotted poor practical predicted prescribed previously probability proposed protocol protocols protons radiology reaching recent related reproducible resolution respectively rise room scale school separately short similarly simple slice slices software spatial studies submerged suitable summary suppression system systematic taken temperature tensor theory thinner traumatic treatment truncation units useful varied variety visible vital water wide