Meeting Banner
Abstract #1899

Localized High Resolution DTI of the Human Brain Using Parallel Imaging and Outer-Volume Suppression at 7T

Christopher J. Wargo1, John C. Gore1

1Department of Radiology and Radiological Sciences, Vanderbilt University Institute of Imaging Science, Nashville, TN, United States

In this abstract, outer volume suppression (OVS) is combined with SENSE parallel imaging to accelerate diffusion tensor imaging (DTI) in the human brain at 7T. OVS provides additional reduction in the DTI data set beyond that achieved using SENSE by constraining the FOV to localized regions in the brain, targeting specifically the midbrain, lentiform, and basal ganglia. In-plane resolutions of 1mm x 1mm x 2 mm were acquired using six diffusion directions and a b value of 1000 s/mm2. Resulting DTI-OVS images are of high quality with minimal or no artifacts using a single shot EPI sequence, enabling localized FA and ADC measurement.

Abstract PDF

Keywords

achieve acquisition acquisitions assessed basal blurring brain capsule challenge codded coded coil color connectivity constraint coronal corp definition design diffusion diffusivity diminish diminished disease distortion distortions dropout duration durations enabling exception excite explore fold form frequency ganglia geometric gore gradient gradients highly hippo human identification identify inform injury insight john largely lent linear localized long loss mapping maps minimal modulated motion narrow necessitating offers optic orientations outer overall pair parallel patient physiological plied pons potential potentially principal produced prov pulse pulses quality receive reduced reduction repetition repetitions required resolution resolutions science sciences sense sensitive separately shot sign slab slabs slight strengths structures subjects suppression system target targeted tensor tissue variations various visible warping white