Diffusion in the Extra-Cellular Space of the Rat Cerebral Cortex Probed by MRI and Direct Infusion of Contrast Agents

Keywords

absence accuracy acid agar agent agents agreement aims alteration anatomical anesthesia apparent applied artificial bandwidth beyond bolus brain burr calculation capillary causing cellular cerebral circles clearance close closed coefficient coil compliance concentration connected consisted contrast control coronal cortex course currently curves cybernetics dashed delivery depth determined diffusion direct dissolved distance distribution doped experiment explore extra feasible fitted fitting fixed flash fluid function fused glass health heart holder hole identified implanted included induced influenced infused infusion initial initially injected injection institutes inversion investigate investigating least limited linear linearly local locally locker long macromolecules made mathematical measured methodology minutes modeling numerical phantom physiological pixel position positioned positioning post presence pressure primary prior probably properties proposed pump rats read real recovery related remained repetition reported scanner sensitivity sensory shape shot silica site slow solution source space spatial square squares step strongly structure studies substances surface temperature temporal theory tissue tool variable volume wash wise