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Abstract #1798

1H-MRS Study of Neurochemical Profiles of Human Primary Glioblastoma in Mouse Models at 9.4T

Abhishek Banerjee1, Tomoyuki Mashimo1, Sandeep K. Ganji1, Kim Kangasniemi1, Todd Soesbe1, Elizabeth Maher1, Robert Bachoo1, Changho Choi1

1University of Texas Southwestern Medical Center, Dallas, TX, United States

 

Keywords

accurate acquisition agreement alanine anesthetized animals anticancer artifacts axial benefit blower body bore brain breast built cell cells clear clinical coil collected concentrations consistent corrected deviation diameter dissociated drift eddy effective elevated elevation enhanced fast feasible field frequency gaining gently glutamate glycine hence home horizontal hours house human identical identify implanted implies in vivo initiating injected injecting investigate isolated localization loss lung magma maintain malignancy masses medical metabolite metabolites metastasis mice model models monitored mouse neuronal normalized observations opposed oxygen pattern phantom popularity population positioned post preliminary prepared press previous primary prior processing profiles proton pulse pulses quantification quantify receive reduced reduction reflect reflected reliable report reported represent representative resection residual residuals resolution respectively respiration sampling scanner scenario separated separation several significance significantly simulated simulation software southwestern spatial spectra spectral spin studies substantially supported suppressed suppression surface temperature throughout together transmit tumor tumors types unlike unpaired unsuppressed various viable vitro water ways whole