High Sensitivity Detection of Targeted PFOB Nanoparticles Binding in a Carcinoma Mouse Model Using a New Diffusion-Weighted Spectroscopy Sequence

Keywords

ability acquisition acquisitions adiabatic agents anatomical anesthetized animal animals anisotropy array background bandwidth binding birdcage blood blue bound broadening calibration cancellation cancer carcinoma cell cells challenging clearance clearly close coil colon combining comes coming commissariat comparing complex concentration concentrations constraints context dashed days dedicated delay delineated described despite detect detecting detection developed diffuse diffusion division echoes effective emerged emulsion encouraging excellent experiment expression flowing full gain grafting in vivo individual injecting injection insensitivity inside integration lack laser leading linear localization long loss mainly materials mice model modulation module molecular mouse nude original part particles peak peptides persistence phantom placed pool positioned preliminary presence previously probably processing properties pulses quantify receiving receptors refocusing robustness rodent sample scanner scheme selective selectively sensitivity short slices specifically spectra spectral spectroscopy spectrum spin spleen spoiling subcutaneously subsequent suggests superposition suppress takes targeted targeting thanks together train tumor twelve unbound vessels visible wait waters weak whereas white yielding yields