Model Free Approach to Kinetic Analysis of Real-Time Hyperpolarised 13C MRS Data

Keywords

acid acknowledgments administered allowing alone apparent application applied aqueous assessing association bottom buffer cancer carcinoma cell cells coefficient commonly comparable computer consistent constant constants containing correlation courses curve curves days derived detect detected determine determined display dissolved division domain dose dots drug dynamic early enriched enzyme equations equivalent error every exchange experiment expertise final fits fitted forward foundation free governing health highly hill hospital house human implantation in vivo indicated indicating induced inhibitor injection institute integrals integrated kinetic kinetics kingdom lactate lateral leach martin measure measured measuring metabolic metabolite metric mice mixed model modified nuclear offers overlaid peak plotted post potentially profiles proportional propose prove radiotherapy reaction real recorded reflects reporting response robust sample scanned selected selective sensitivity series sets site situ slice sodium solution spectra spectral spectrometer studies subcutaneous subcutaneously suggested support surrey suspension tail therapy transient treated treatment treatments trust types typically upon useful variety various vein vitro wide width wing