Real-Time In-Vivo Metabolic Characterization in Spontaneous Hepatocellular Carcinoma Using a Novel Transgenic Mouse Model

Keywords

aberration according acid activity addition advanced advocates alanine amino animals another aspect assay axial axially beauty began begins biochemical biology brings cancer carbon carcinoma carcinomas categorized cell cellular characterization clearly clinical clinically collected combination comprehension conditions containing course crucial cycle developed development dissolution distinct distinguished emerged empowering enabling encoding energetics ensure environmental enzyme flux fluxes form functional gradient healthy heated hepatitis human hypoxia identified illustrates illustrating immediately implemented in vivo induced infusion insights institute intravenous invaluable investigation labels lactate like liter live liver livers matrix measure metabolic metabolism metabolite metabolites mice might mimic model models molecular months mouse novel observing obvious offers package pathological peak physiological polarization post potential pressurized probe processing progression proton prove quantification rapid real reduction respect revolutionary sacrificed sample selective sensitivity significantly sleeping slice sodium solution space spatial spectra spectrophotometric spectroscopy spontaneous stage stages starts studies subsequently successfully suggests sweep system technology transform unprecedented upon useful width yield zero