Passively Masked Surface Charge of SPIO Nanoparticles for Specific Detection of EGFR Expressing Tumor Cells

Keywords

abstract achieve acid agent agents aimed antibody applied binding biological buffer buried cancer cancers carcinoma carried cell cells chains charge charged charges chemical chimeric clearly confocal conjugated consequently contrast control decomposition decrease deep derivative design designed detection developed development diagnostic dual early easily efficacy electrostatic engineering enhance enhances entangled epidermal exchange exemplified expressing expression facile finding fluorescence furthermore generation gong growth hand head highly human hydrophilic hydrophobic incubated induce inertness innovative inside insulator intensity interaction iron ligand masked masking materials membrane membranes metastatic microscope ming modalities modality monoclonal national natl neck negative negatively next nonspecific novel ones optical overcome oxide passive passively positive post potentially problem properties quantitative reaction reactive receptor reduce reflecting remain replace reported safely scale scanned science sensitive significance simultaneously specificity squamous strategically strategy studies substantial surface surfactants synthesis synthesized targeted targeting technology therapeutic thermal tissue transform treatment tumor tung turn uptake usefulness variation vitro washed