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Abstract #1576

Strategy for Simultaneous Region-Tracking and Temperature-Monitoring in the Liver During Free-Breathing

Bruno Madore1, Matthew Toews1, Chang-Sheng Mei1, Renxin Chu1, W. Scott Hoge1, Lawrence P. Panych1

1Department of Radiology, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, United States

MR-guidance for thermal ablation therapy in moving organs such as the liver is a challenging application, as it requires tracking the region targeted for ablation while simultaneously measuring temperature in and around it. A pulse sequence was implemented that presents advantages over regular gradient-echo and echo-planar sequences, both in its ability to enable motion tracking and to detect temperature changes. A software system was developed combining fast landmark-based image tracking and temperature calculation, and users were asked to visually judge the performance of the software as applied to in vivo data.

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Keywords

abdomen ability accelerated acknowledged actual affect allow allowing anatomy appeared application arguably around asked available averaging blood breathing bright challenging channel circle coil contrasts coverage created deformation detecting detection deviations displacement displacements displayed early employed enable ensuring errors evaluate evaluated expected experiment facilitating fast featured five flow frames free generated great green ground heated heating help hospital human implemented in vivo increasing interval judge judged landmark late length leverage like limited listed liver location locations magnetization medical microprocessor monitoring mostly motion movie negatively next noise object organs overall particularly pathways pinned pixel placed planar plot presence process program proposed pulse quality radiology random reached real reasonable reduce registration related replaced requires scale scanner scheme school score scores select selected selects sensitivity simultaneous slice slightly snapshot spatial spectral spin static step strategy superimposed support suppressed symbol table temperature therapies thermal tissue tracked tracking truth undergoes underlying updated user users version vessels view visually women