Meeting Banner
Abstract #1476

Dynamic Analysis of Breast Lesions: Can We Use the Wash-In Phase Instead of the Wash-Out Phase?

Ritse M. Mann1, Roel DM Mus1, Christian Geppert2, Cindy PM Frentz1, Nico Karssemeijer1, Henkjan Huisman1, Bram Platel1, 3

1Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, Gld, Netherlands; 2Oncology, Siemens Healthcare, Erlangen, Germany; 3Fraunhofer MEVIS, Bremen, Germany

Initial maximum slope of enhancement as derived from ultrafast TWIST images acquired during contrast inflow provides a strong discriminator between benign and malignant disease that outperforms classic 3-timepoint analysis. By using a fixed grid of relative enhancement versus time curve types can be defined that can be easily implemented in current radiological practice.

Keywords

abnormalities achieved acquisitions agent allows analogue assess assessed available axis becomes benign better bilateral breast central channel classic clearly coil consecutive consequently continuous contrast curve curves cutoff decrease define density depicted derived diagnostic differentiate differentiation discriminating discriminator disease document dynamic easily either enhancement enhancing enough equals evaluating eventual everywhere exemplary fast feasible features fixed gives green grid heuristic highest implemented included inflow initial instead interleaved intermediate least lesion lesions light malignancies malignancy malignant materials measured medical minutes modeling morphologic morphology note novel oncology opening outer outperforms pathologically patients performance plateau possibilities practice propose protocol radiological radiology rather readily recorded regarded resolution respectively risk risks sampling scanner scanning screening series serious significantly simple simplification since slope sought spatial specificity stable still strong sufficiently temporal thereby trio twist type types ultrafast upon upslope versus vibe wash washout whole years yields zone