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Abstract #1474

Feasibility of Contrast-Enhanced and High Resolution MR-Imaging in Patients with Suspicious Breast Lesions at 7 Tesla.

Bertine L. Stehouwer1, Dennis W.J. Klomp1, Peter R. Luijten1, Karel A.F. Houwert2, Paul J. van Diest3, Willem P.Th.M. Mali1, Maurice A.A.J. van den Bosch1, Wouter B. Veldhuis1

1Radiology, University Medical Center, Utrecht, Netherlands; 2Radiology, Zuwe Hofpoort Hospital, Woerden, Utrecht, Netherlands; 3Pathology, University Medical Center, Utrecht, Netherlands

Eighteen patients with 21 biopsied breast lesions were imaged at 7T. The protocol included a dynamic series consisting of 7 consecutive 3D T1-weighted turbo field echo sequences and ultra-high resolution imaging with a 0.45x0.57x0.45mm3 acquisition matrix. All 21 malignant lesions were scored according the BI-RADS-MRI criteria by two radiologists, independently, using the dynamic series. Subsequent ultra-high resolution imaging increased reader confidence in n=13 and=9 for the separate radiologists and changed interpretation in n=3 and n=5 cases for the radiologists. Overall, we showed the feasibility of clinical 7T CE breast MRI, and its amenability to BI-RADS-MRI conform analysis.

Keywords

ability according accuracy achieved additional administered allows amenability another applied artifacts assessed assessment biopsied biopsy body breast calcifications cancer carcinoma care classification clumped coil confidence conform consecutive contrast currently curve deemed delayed descriptor detail detected detection diagnoses diagnostic dynamic enhanced enhancement entities exams excellent experienced explored fast feasibility features field final form furthermore future good great health heterogeneous histological histology hospital improve improved included individual influence influenced inhomogeneities inhomogeneity initial instance insufficient interfere internal interpretation irregular isotropic kinetics least lesion lesions limitations little lobular loop malignant margin mass medical moreover negatively next none offers optimized options outcome pathologically pathology patients placed plateau position positioned possibilities potential prone protocol proven providing quality radiologist radiologists radiology rads rapid reader reasons related representative resolution scale scanner scored sensitivity separate separately series setup shape similarly smooth staging strengths sufficient suppression suspicious table technical temp trial true turbo ultra ultrasound unilateral utilizing washout whether whole women