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Abstract #1426

Using DTI to Assess the Effect of Diet or Exercise in Elderly Obese Women

Armen A. Gharibans1, Curtis L. Johnson1, Danchin D. Chen1, Dolores D. Guest2, Christie L. Ward3, Bhibha M. Das3, Ellen M. Evans3, John G. Georgiadis1

1Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States; 2Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL, United States; 3Kinesiology, University of Georgia, Athens, GA, United States

Diffusion tensor imaging (DTI) was used to study microstructural changes in the thigh muscles of elderly, obese women before and after a diet or exercise intervention. Nineteen subjects underwent either a diet or a weight-stable exercise four-month program. Both weight loss and exercise regimens alter muscle microstructure and modify various DTI measures, but exercise impacts muscle quality more than weight loss.

Keywords

acquisition aging aiming anisotropy apparent arbitrary assess blocked body caloric champaign channel choice coefficient cohort coil combination combined community computed concomitant consensus consisted consistently constant containing contention correlated correspond course cross dataset decrease decreased device diet diffusion dimensional dividing eccentricity effective efficacy eigenvalues either elderly ellipsoid endurance engineering exercise experimentally explained explores extension fiber fitness flexible force fractional goal health improving increasing index intervention interventions invasive involving kcal knee lean least linear loss magnitude matrix measures measuring mechanical midpoint minute modalities month muscle muscles negatively nineteen obese operator ordinary package participated peak period perturbations physical physiological planar population position post program pronounced prospect pulse quadriceps quality quantify refocused related remained restriction sectional separated sessions seven shot skeletal slices software spatial spectral spin spine squares stable strength structure student subjects supervised suppressed surface table tabulated tailed tensor thigh thighs toolkit torque training twice unchanged units unlike variances various ward week women years