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Abstract #1376

Clinical Evaluation of CAIPIRINHA: Comparison Against a GRAPPA Standard

Michael W. Harrell1, Katherine L. Wright2, John Jesberger, 13, Luis Landeras1, 3, Dean Nakamoto1, 3, Smitha Thomas1, 3, Dominik Nickel4, Randall Kroeker4, Mark A. Griswold2, 3, Vikas Gulani1, 3

1School of Medicine, Case Western Reserve University, Cleveland, OH, United States; 2Dept. of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; 3Dept. of Radiology, University Hospitals of Cleveland and Case Western Reserve University, Cleveland, OH, United States; 4Siemens Medical Solutions, Erlangen, Germany

CAIPIRINHA (Controlled Aliasing In Parallel Imaging Results IN Higher Acceleration) is an imaging technique that modifies aliasing artifacts during image acquisition, which potentially allows for a more robust parallel imaging reconstruction with fewer aliasing artifacts. Here this was tested by comparing CAIPIRINHA against a clinically standard GRAPPA acquisition for highly accelerated breath hold liver scans. Evaluation of the image quality of CAIPIRINHA by three blinded, untrained radiologists demonstrated a statistically significant improvement in clinical image quality in comparison to a standard GRAPPA.

Keywords

abdomen abdominal accelerated acceleration acquisition added advancements agreement aliased aliasing allow allows altering among another application applying arrow artifacts asked attending bandwidth biomedical biometrics black blinded body breath choice chosen clinical clinically combinations compliance comply confidence contrast controlled correlation critical dean decrease depicted dept differed displayed encode encoding engineering evaluate evaluation exam except experience fellow fewer five forced goal good gradient grants highly hold hospitals impact important improved improvement interval intraclass kappa known leading limitations liver location long made mark medical modified modifies month nickel noise offsets overall parallel partition patients pattern patterns period pixel poor post preference produce propose quality quantity quiescent radiologists radiology ranks rater raters ratings readers reconstruction reduced reduces reduction reliability reordering requirements reserve residual resolutions robust sample sampling scheduled school select selected selections sets severity significantly slice spatial specifically statistic statistical statistics strategy studies summarized summer trained validate versus western whether white wide written year years