Meeting Banner
Abstract #1344

Oxygen Enhanced Lung MRI Using 3D Radial UTE SPGR in Humans

Stanley J. Kruger1, Kevin M. Johnson1, Sean B. Fain1, 2, Robert V. Cadman1, Laura C. Bell1, Scott K. Nagle1, 3

1Medical Physics, University of Wisconsin, Madison, WI, United States; 2Biomedical Engineering, University of Wisconsin, Madison, WI, United States; 3Radiology, University of Wisconsin, Madison, WI, United States

Oxygen Enhanced MRI of lung parenchyma has so far relied on a SSFSE sequence paired with an inversion recovery to mitigate T2* decay and provide ample contrast in the low signal environment. Coverage is often limited, and multiple acquisitions are required to obtain adequate SNR. Radial 3D UTE-SPGR is a new technique in oxygen enhanced MRI that combines oversampling the center of k-space as well as short TE to yield a 3D isotropic volume of oxygen enhanced signal that is robust against cardiac motion artifact and T2* decay, while providing full lung coverage in any orientation.

Abstract PDF Poster PDF

Keywords

able absence acceptance accessible acquisition adaptive aortic apparent approved arch arrows artifacts available averaging axial bellows biomedical blood breathing built cardiac chambers channel chest clinical coil collected commercial comparable compliant contrast coronal coverage creating decay deformable degrades delivered density designed discarding dual efficiency engineering enhanced enhancement environment equation expensive expiration fain fast feasibility feedback filtered fitting free full furthermore gated generated gradient gradients great hardware heart holds human humans improve improving include included incomplete inexpensive inherent inversion isotropic linear lobe long lung marked mask matrix maximize medical minimized mitigating mixture model molecular motion noble oxygen oxygenated parallel paramagnetic partial pause percent phys physics pixel potential previously projections promise promising prospective proton pulmonary quality radial readout real recalled recent reduces relied reported resolution respiratory robust short shortening shot simple slice slices space spin spoiled subject subjects success sufficient systole thick tidal tight trajectory transient true ultrashort utilized utilizes variable ventilation view widely