Meeting Banner
Abstract #1305

MR Elastography (MRE): Evaluation of New Inversion Algorithm and Quantitative Analysis Method

Alvin C. Silva1, Annelise M. Silva2, Roger C. Grimm3, Kevin J. Glaser3, Amy K. Hara1, Richard L. Ehman3

1Radiology, Mayo Clinic Arizona, Scottsdale, AZ, United States; 2Xavier, Scottsdale, AZ, United States; 3Radiology, Mayo Clinic Rochester, Rochester, MN, United States

MR Elastography is a promising, noninvasive technique for discriminating normal from diseased liver, including fibrosis stage. With the introduction of a new inversion algorithm (MMDI) and confidence mask, suggested published threshold values in this regard may have to be modified. The purpose of this study is to compare calculated mean shear hepatic stiffness calculations (kPa) between the two inversions algorithms and assess inter- & intraobserver variability between two measurement techniques (ie, confidence threshold mask versus free-hand ROI).

Keywords

acoustic addition adequate admission advantage anatomy approval asses assessment avoiding beers biopsy board bring calculation calculations called carcinoma chronic clinic coefficient complications conference confidence correlate correlation created creating currently dashed dataset defined detect direct discriminating disease diseased donors drawn driver either elastic elasticity emerging error etiology evaluation fibrosis forth free freehand generate gold hand healthy hepatic highlighting hospital human hypertension impacts individual institutional inter intra intraclass invasive inversion inversions issues liver localizing longitudinal mask mayo mechanical median model modification mortality need newer observer occurs orange organ outpatients painful pasted patients periphery placed pneumatic portal positioned preliminary processed processing prolonged prone propagating propagation properties quantified quantify quantitative radiology reduces regardless relatively remains repeat repeated report require requiring resolution response resultant review risk roger sampling scale sets shear stage stages standardized stay stiffness strain strongly suggested superimposed takes technology therapy threshold tissue transplant twice ultrasound valid variability variance versus waves weeks white yang