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Abstract #1298

The Usefulness of Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC) Value for the Diagnosis and the Assessment of the Therapeutic Effect on Autoimmune Pancreatitis (AIP)

Keizo Tanitame1, Yuko Nakamura1, Yoko Kaichi1, Chihiro Tani1, Yukiko Honda1, Miyuki Takasu1, Kazuo Awai1

1Diagnostic Radiology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan

Problem: To compare the ADC values of AIP and pancreatic carcinoma and investigate their usefulness in IgG4-related AIP during steroid therapy. Methods: ADC values were compared among 10 patients with IgG4-related AIP, 7 with IgG4-negative AIP, 27 with carcinoma. In 6 patients with IgG4-related AIP ADC values were followed during steroid therapy. Results: The ADC values were significantly lower in IgG4-related and -negative AIP than carcinoma (p<0.01, each). ADC values increased during the therapy in all patients with IgG4-related AIP. Conclusion: ADC value was useful for differentiating between AIP and pancreatic carcinoma and for assessing the effects of steroid therapy.

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Keywords

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