Meeting Banner
Abstract #1291

Magnetic Resonance Imaging of HCC: Predictive Findings of Post-Transplant Tumor Recurrence in a Screening Population

Bobby Kalb1, David Becker-Weidman2, Surya Chundru1, James Costello1, Puneet Sharma1, Khalil Salman1, Hina Arif1, Diego R. Martin1

1Radiology, University of Arizona, College of Medicine, Tucson, AZ, United States; 2Radiology, Emory University Department of Medicine, Atlanta, GA, United States

Reduction of post-transplant recurrence of hepatocellular carcinoma (HCC) is optimized by strict pre-transplant tumor staging (Milan criteria); however post-transplant tumor recurrence still occurs in up to 10% of patients with optimal preoperative staging. Imaging methodologies that are better able to predict recurrence risk of HCC from pretransplant imaging would be valuable in the triage of donor organs. Our study investigates potential imaging features on MRI that may provide added prognostic information regarding the biological behaviour of HCC, with the aim to better predict posttransplant recurrence.

Keywords

accurate additional adjacent approved approximately arterial assessed assessment available background better beyond blinded bobby body capsule carcinoma chronic clinical collected college common compliant complication criteria curative days degree despite determine disease early either elevated eligibility enhanced enhancement evidence exact experts exploratory extent extremely features findings fisher foundation frequency governed hepatic histological identification identified included intensity intervention lancet lesion lesser lipid listed liver martin materials medicine outcomes outside overall pathologic patient patients population post potential predict predicting predictive predictor predictors preoperative presence priority qualitative qualitatively radiology rank records recurrence recurrent reduce related relatively remains respect retrospective retrospectively reviewed risk scale score scored scoring screening staging survival though transplant transplantation transplanted triage tumor tumors underwent validated valuable