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Abstract #1287

Fast T1 Mapping for Liver Function Estimation Using Gd-EOB-DTPA

Tetsuya Wakayama1, Keizo Miyakoshi2, Daisuke Nishiyama2, Masahiro Okada3, Hiroyuki Kabasawa1, Tatsuro Uto2, Takamichi Murakami3

1Global Applied Science Laboratory, GE Healthcare, Hino, Tokyo, Japan; 2Department of Radiological Technology, Kinki University Hospital, Japan; 3Department of Radiology, Kinki University Faculty of Medicine, Japan

A novel approach to three dimensionally measure T1 value of liver with IR-based multiple breath-holding acquisitions was developed and demonstrated in this study. The phantom validation revealed that 3D T1map developed here could provide acceptable accuracy of T1 with larger volume coverage and less scan time, compared with 2D T1map acquired by conventional 2D IR-FSE. In volunteer examination, 3D T1map was successfully obtained from liver. This approach can be expected to three dimensionally evaluate T1 of the liver with clinically acceptable scan time.

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Keywords

abdominal acceptable accuracy acquisition acquisitions addition administrating allowed applied approximately authors breath challenging clinical clinically concentrations conducted consistent consists correlation coverage designed detailed develop developed diagnostic diluted dimensional dimensionally dramatically edition especially establish estimation evaluate except expected faculty fast fitting function functional global gold good healthy hold holding hospital institution invest japan laboratory larger least linear liver mapping matrix measure medicine novel numerical phantom plot prep press previous previously protocol prototype pulse quantitative radiological radiology rapid recipes reconstructed reported respective respectively saline scanner science selective separated sets slice slices software solution squares successfully technology typical uniform useful validation various verify volume volunteer volunteers wide