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Abstract #1256

magnetic Resonance Elastography of the Human Abdominal Aorta: A Preliminary Study

Lei Xu1, 2, Jun Chen1, Kevin J. Glaser1, Meng Yin1, Phillip J. Rossman1, Richard L. Ehman1

1Radiology Department, Mayo Clinic, Rochester, MN, United States; 2Radiology Department , Beijing Anzhen Hospital, Capital Medical University, Beijing, China

To investigate the feasibility of using MRE for the evaluation of the mechanical properties of the in vivo aortic wall. The feasibility of performing pulse-gated cine MRE technique in the abdominal aorta was assessed in five healthy volunteers. In the study, the waves were well visualized within the lumen of the abdominal aorta in the diastolic phase, but they were not well visualized during systole. A significant correlation between E*t product of aortic wall in the five volunteers and their age was revealed (r2=0.81). The study shows that MRE is feasible for assessing the elastic properties of the abdominal aorta.

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Keywords

abdomen abdominal aneurysms aorta aortic applied arterial assess assessed believe beneficial buffering capital china cine clinic correlation cycle determine determining development diastole diastolic diseases driver early elastic elasticity emphasis evaluate evaluation even experimental external feasibility five flow fluid formation gated gradient great healthy heart human in vivo investigate largest lumen major makes male masked mayo measured mechanical medical ming modulus motion need noninvasive offers passive people phantom placed porcine posed potential preliminary presence pressure prior produced product prop propagation properties pulse reason regional related relationship republic risk role rupture shear static stiffness studies thoracic transmitted vessel visualized volunteers wall wave waves years