Meeting Banner
Abstract #1210

Non-Contrast-Enhanced Vein Imaging in the Deep Veins: Impact of Velocity Patterns and Improved Image Quality

Andrew Nicholas Priest1, Martin John Graves1, David John Lomas1

1Department of Radiology, Addenbrookes Hospital and Cambridge University, Cambridge, United Kingdom

MRI has the potential for multi-contrast imaging of venous thrombo-embolism (VTE). Luminal imaging may be performed using ADVANCE-MRV, a recently developed method which relies on suppression of flowing signal using an iMSDE preparation module. It is demonstrated that signal suppression is governed both by the flow velocity and by velocity dispersion. In low-dispersion situations, the signal may oscillate as a function of velocity, leading to signal loss from the subtraction venograms. This effect is investigated in volunteers, and an image combination method is proposed, leading to more uniform vascular images despite flow variations.

Keywords

absence acceleration achieve achieved acquisitions additionally affect aims amplitude anatomy apparent applied apply appropriate approval approximately arterial arteries artery back background balanced biomedical blood blue carried charitable chosen combination combined combining component consent contrast coronal dataset deep delay dependent detailed dimensions dispersion edges effective either enable enhanced ethical evenly example exhibiting expressed expression flow flowing fluctuations frequency function functions funding give gradient gradients graphs greatly guarantee healthy highly illustrated impact impaired imperfect important improved in vivo increasing increasingly initial investigate john linear little location locations loss martin materials matrix module moment moments near occurs orientation oscillations oscillatory particularly patterns peak placed preparation press priest profiles pronounced pulse quality readout real recent reduced reflects related relevant represent represents respectively rotated sensitive sensitivities several simulates since spaced spoil steps studies subtracted subtraction successive suppress suppressed suppression system take thank theory thereafter though thrombus uniformity variation varying vascular vein veins velocities velocity venous vessel voids volunteers