Meeting Banner
Abstract #1138

A Model-Based Approach for Deformable Registration of Ungated Cardiac Perfusion MRI

Ganesh Adluru1, Alexis Harrison2, Chris McGann2, Edward V.R. DiBella1

1Radiology, University of Utah, Salt Lake City, UT, United States; 2Internal Medicine, University of Utah, Salt Lake City, UT, United States

Cardiac perfusion MRI without ECG gating can be a promising alternative for imaging patients with atrial fibrillation and for imaging at high field strengths. Self-gating techniques can be used to retrospectively bin ungated images into approximate systole and diastole. However cardiac and respiratory motion can still be present in these self-gated images. Here we propose a model-based deformable registration approach that uses a two-compartment contrast model to remove the residual motion. A model reference image for each image in the dynamic sequence is generated and deformable registration using a finite element based method is performed to obtain motion free images.

Abstract PDF Poster PDF

Keywords

account acquiring acquisition allow alternatives ants applied applying approx approximate around arterial assessment axis binned binning blood blur blurring body bottom brain cardiac chart city compartment compartmental computed constrained constraints continuously contrast correcting corrects corroborated curves deformable described diastole diastolic differ directly drastically efficient evaluation except field final finite fitted five flow fluctuations formulate frame frames framework function gate gated gating generated good green heart heartbeats horizontal idea identified improved input intensity irregular lake local matrix minutes model motion myocardial myocardium navigator note ones opposed original parallel patients perfectly perfusion pixel pool pools procedure processed processing profile profiles promising propose proposed quantification radial radiology recently reconstruct reconstructed reconstruction recovery reduce reduced reduction registered registering registration registrations replacing represent respectively respiratory rigid salt saturation scanner seek self separately short since slice slices sophisticated spline step still strengths studies summary summing suppressed suppression systole take temporally toga variation variations ventricular vertical waiting warping