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Abstract #1125

Assessment of Myocardial Triglycerides by 2D PRESS Echo-Planar Spectroscopic Imaging

Jan Weis1, Morten Bruvold2, Francisco Ortiz-Nieto1, Hkan Ahlstrm1

1Department of Radiology, Uppsala University Hospital, Uppsala, Sweden; 2Philips Healthcare, Best, Netherlands

Cardiac and respiratory triggered 2D PRESS echo-planar spectroscopic imaging with high spatial resolution was used for the assessment of triglyceride content in the human myocardium. The PRESS volume of interest selection enables smaller field of view and minimizes signal contamination from outside the PRESS box. The proposed data processing approach using magnitude spectra avoids the need for individual phase correction before voxel spectra averaging. High spatial resolution enables evaluation the local triglyceride changes in non-continuous and irregularly shaped volumes of interest.

Keywords

acquisition aged agreement applied arising artifacts assessment averaging axis band bandwidth beginning belt best black body boxes cardiac caused choline circular coil complex computed consent contaminated contamination content continuous corrections depending depicts diabetes diastole dimensions done double echoes effective element enables estimations evaluation excitation explained field fitted folding gating glucose gradient gradients healthy heart highest human impaired individual input integrals interleaved introduce inverse iterative limitations lipid local magma magnitude mass materials matrices matrix measured middle myocardial myocardium need nominal obese optimized outside overweight parts patients period planar position positive practically press pressure problems processed processing projected proposed pulses quality quantities radiology read readout real receiver rectangles reduce regional relatively reliable repetition resolution resp respectively respiratory rest saturation scanner selection selective shaped shimming slice slices solution spatial spectra spectral spectroscopic storage suppress suppressed suppression thin tolerance tool train trains triggered triggering triglyceride triglycerides unsuppressed usefulness usually utilizing volume volumes wall water white