Meeting Banner
Abstract #1113

Multi-Slice Saturation-Recovery Look-Locker Method for Rapid T1 Mapping of Mouse Myocardium

Kai Jiang1, 2, Xin Yu1, 2

1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; 2Case Center for Imaging Research, Case Western Reserve University, Cleveland, OH, United States

An ECG-triggered multi-slice saturation-recovery Look-Locker (MSRLL) method was developed for fast cardiac T1 mapping. High temporal resolution (2.5 minutes) was achieved without the aid of parallel imaging or EPI. Phantom and in vivo validations were performed by comparing measured T1 with that using the single-slice Look-Locker method.

Abstract PDF

Keywords

accurate acquisition acquisitions additional agreement allowed among anesthetized applied assessment axis beats beginning biomedical cardiac centrifuge coil compartment complete continuous contrast cost curves cycle delay developed diameter diastole dynamic eliminate engineering enhanced equivalent every fast flash generally good heart horizontal in vivo inner intensity interval intervals late locker long longitudinal look magnetization maintained mapping maps matrix measured mice minimize minutes month motion mouse myocardial myocardium period phantom physiological previously protocol pulse pulses quantitative ranging rapid recovery reflects relatively repetition representative requirement requires reserve resolution respectively robust saturation scanner sealed separated sequential short slice slices solutions strong studies temporal trigger triggered tubes validated validation ventricular vitro volume western whole