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Abstract #0947

Manganese-Enhanced MRI for Phenotyping Brain-Wide Activity in a Mouse Model of Emotional Learning & Memory

Hadley Bergstrom1, Haiying Tang2, 3, Jennifer McGuire3, Asamoah Bosomtwi3, Luke Johnson1, 3, Afonso Silva4, Reed Selwyn2, 3

1Psychiatry, Uniformed Services University, Bethesda, MD, United States; 2Radiology, Uniformed Services University, Bethesda, MD, United States; 3Center for Neuroscience and Regenerative Medicine, Uniformed Services University, Bethesda, MD, United States; 4National Institute of Neurological Disorders and Stroke, National Insitutes of Health, Bethesda, MD, United States

 

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Keywords

ability achieve activation activity additional administered alterations analyzed anesthesia animal array behavior behavioral believe body brain bred cage cell centrally chloride coil components concentration conclude conditioned conditioning control corp correlate correlated correlation cortex delivering dependent develop diameter disorders dissolved dose dosing duration embedded emotional enhanced enhancement enter except fast fear find finding flash flow functional functioning future generations greater hand head health heart heating holder home horizontal hypothalamus hypothesized immediately implant implanted in vivo inner institute intensities intensity involved isotropic lack layer learning likely loaded magnet manganese matches measured medulla memory mice minimize model mood multivariate national necessary neural next normalized optimal osmotic parallel particular percentage phenotype prepared price protocol psychiatry pump pyramidal quadrature quantitatively radiology rare reed regenerative related represent resolution scanning scientific selectively services significance statistical statistics stroke subcutaneous subject subjects suggest superconducting system tang temperature temporal thought tool transmit underlying uniform uniformed unrelated uptake valuable variable variations various voltage wide