Diffusion Tensor Imaging Detects Progressive Brain Damage in a Murine Model of Chronic HIV-1 Infection

Keywords

accordance acquisition aged alterations analyses animals anisotropy aspects assessment attributable balanced barrels barrier bilaterally blood brain care cell cells cerebral chronic coil combat commonly conjunction control controls correlated cortex course culture dash decrease decreased decreases degeneration degradation degree designed detects developing diffusion diffusivity disease disorders dose doses effectiveness encoding establishment ethical examined experimental fast fractional gated gradient guidelines herein human humanized humans icosahedral immune include includes indicate infected infection infectious ingress injected injection institutes investigated irradiated journal laboratory largely leads likely linear load loss macrophage matrix maturation medical meningitis metrics mice miller model mouse national negative nervous neuronal newborn null official organization path pharmacology planar polarity post procedures progressive purified radial radiology receive reductions regression regressions resolution respiratory revealed reveals rotationally seven shot slice slope slopes spectrum stem strongly structures subregion surface sustained synapses system tensor termed therapies tissue transmit transverse twice ultrahigh uninfected versus viral water weeks whisker whose zero