Meeting Banner
Abstract #0872

Quantitative MR Imaging of Brain Tumors: A Step Forward?

Dita Wagnerova1, Vit Herynek1, Alberto Malucelli2, Monika Dezortova1, Josef Vymazal3, Dusan Urgosik4, Martin Syrucek5, Filip Jiru1, Antonin Skoch1, 6, Robert Bartos2, Martin Sames2, Milan Hajek1

1Department of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 2Department of Neurosurgery, JE Purkyne University and Masaryk Hospital, Usti nad Labem, Czech Republic; 3Department of Radiology, Na Homolce Hospital, Prague, Czech Republic; 4Stereotactic and radiation neurosurgery, Na Homolce Hospital, Prague, Czech Republic; 5Department of Pathology, Na Homolce Hospital, Prague, Czech Republic; 6International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic

The specific correlation patterns between metabolic values, mean diffusivity and T2 relaxation times based on multivoxel analysis were observed for low and high grade gliomas, lymphomas, recurrent lesions and tissue changes by radiation/chemotherapy which enable not only tissue differentiation (healthy tissue, edema, tumor infiltrated edema, tumor; tumor recurrence vs. radiation necrosis), but also tumor type differentiation. Combination of several MR methods can be used for quantitative description of tumors to improve the outcome from MR examination of patients.

Keywords

able according active artifact assessed automatic better biochemical biopsy brain caused cells cellular certificated characterized chemical chemotherapy clinical coil combination consent consequent considered consisted consists control correlation correlations corresponds days decided dense describe diagnosis diagnostic differentiating differentiation diffusion diffusivity distinguish distortions echoes edema edematous enhancing equipped examination examined exhibit experimental extent fluid forward frame grant gray green guided head healthy help heterogeneous highly hospital house hypothesize identification improves infiltrated informed inside institute international intracellular involved lactate leading least lesion lesions linear lipids localization lymphomas macromolecules martin mater metabolic mode navigated necrosis neurosurgery norm open origin pathological pathology patients pattern patterns pixel positive potential precise primary program projects prospective protocol protocols proximity quantitative radiation radiologist radiology radiotherapy recurrence recurrent remaining republic resection resp sames schematic semiautomatic shrinks sites slice space special spectroscopic step subjects subsequent suitable swelling therapy tissue tumor tumors type types unavoidable understanding untreated utilizing validate vicinity violet water whole