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Abstract #0859

Quantitative 2D Chemical Shift Imaging of Glutamate in Brain Tumour Patients

Bradford A. Moffat1, Liubinas Simon2, Katherine Drummond2, Andrew Morokoff2, Terrence O'Brien3, Chris Kokkinos4, Patricia M. Desmond1

1Radiology, University of Melbourne, Parkville, Victoria, Australia; 2Surgery, University of Melbourne, Parkville, Victoria, Australia; 3Neurology, University of Melbourne, Parkville, Victoria, Australia; 4Radiology, Royal Melbourne Hospital, Parkville, Victoria, Australia

Glutamate concentration in human brain tumours has been quantified from 2D CSI PRESS imaging. We present HPLC validation of this technique. A High Correlation with HPLC data suggests 2D CSI is an excellent biomarker of in vivo Glutamate concentrations.

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Keywords

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