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Abstract #0719

High Resolution Functional Mapping of Spatiotemporal Vibrotactile Stimuli Reveals Differential Areal & Laminar Activations in Somatosensory Cortex

Robert Friedman1, Feng Wang1, Chaohui Tang1, Anna Roe1, Malcolm Avison1

1Vanderbilt University, Nashville, TN, United States

We used high resolution CBV fMRI to examine the role of inter- and intra-areal processing of spatiotemporally varying tactile inputs in somatosensory motion perception. Simultaneous stimulation of three adjacent digits elicited weaker, more focal activation in area 3b of SI somatosensory cortex than would be predicted from single digit responses. Sequential tapping elicited greater than expected activation in areas 3b and 1. In areas 3b and 1, single digit and simultaneous multiple digit stimulation activated mid-cortical layers, whereas sequential tapping of the digits evoked significant activation in superficial and deep laminae.

Keywords

activation activations activity actuators adjacent amplitude anesthetized apparent areal began blocks bolus bottom coil collected columnar compatible conditions consisted contrast coronal correlates cortex cortical cortically delivered determined differently digit digits distal duration dynamics either eliciting evoked evoking examine expected exploited extent features filters findings finger frame frequency functional funneled funneling generate gradient gray greater head identically identify illusion illustrate individual individually infra instance intervals laminar layer layers linear locate located maintained mapped mapping maps matrix mechanically middle milliseconds monitor monkeys motion network neural noise oriented pads parallel percept perception perceptual poorly positioned predicted primary procedures processing receive reflected relationship resolution response responses reveal revealed reveals runs scanner sensation sensory sequent sequential sequentially series session sessions shot simultaneity simultaneous simultaneously sites skin slice slices spanned square squirrel stabilized stimulation stimuli stimulus strengths structural structures studies suggest surface tactile tapped tapping taps temporal thresholded trans transmit uncorrected understood venous ventilated vital wave wide