Meeting Banner
Abstract #0627

Free Breathing Ultra-Echo Time Lung Imaging with Variable Density 3D Radial Sampling

Kevin Michael Johnson1, Scott K. Nagle1, 2, Sean B. Fain1, 2

1Medical Physics, University of Wisconsin-Madsion, Madison, WI, United States; 2Radiology, University of Wisconsin-Madison, Madison, WI, United States

Detailed lung structure is poorly visualized with conventional MRI due to low tissue density and rapid signal decay. Ultra-short echo time (UTE) imaging has long held promise to dramatically enhance signal from short T2/T2* species. Due to a long T1 and low tissue density, 3D UTE lung imaging remains extraordinarily sensitive to artifacts from Gibbs ringing, physiological motion, eddy current induced errors, and low signal to noise ratio (SNR). In this work, we develop a robust technique for free-breathing, high-resolution 3D UTE imaging that aims to mitigate sources of diagnostically obscuring artifacts.

Keywords

acceptance adaptive aliasing animals arms artifacts assessment assistance attempts bandwidth bellows breathing calibrations cardiac cardiopulmonary coil collect combination compensation conditions consistency coverage decay define demonstrating density designed despite diagnostically diagram direct double dual eddy effectively efficiency emerging enabling enhance excitation fain feedback fibrosis free full gain gating gradient gradients greatly gurney hardware highly human improve improvement improvements improves improving incomplete inferior invasive isotropic length limit long lung medical minimized mitigate motion noise objects obscuring optimization outside oversampled oversampling penalty perfusion potential prescribed progressive projections promise proposed pulmonary pulse qualitative quality quantitative radial radiology ramp random rapid readout readouts real receive reconstructed reduced reduces remained representing required resolution respiratory retrospectively robust sampled sampling sense sensitive sensitivities sharpness short shorter slab sources space species steady structural structure structures studies subject subjects subsequently support switch theoretical thin threshold tissue trapezoid ultra unmodified utilize utilized utilizes utilizing variable variety view visualized volume volumetric volunteers window