Meeting Banner
Abstract #0609

Implementation & Validation of Fast Whole-Brain B1 Mapping Based on Bloch-Siegert Shift and EPI Readout

Qi Duan1, Souheil J. Inati2, Peter van Gelderen1, Sunil Patil3, Jeff H. Duyn1

1Advanced MRI section, LFMI, NINDS, National Institutes of Health, Bethesda, MD, United States; 2Functional MRI Facility, NIMH, National Institutes of Health, Bethesda, MD, United States; 3Center for Applied Medical Imaging, Siemens Corporation, Corporate Research, Baltimore, MD, United States

Mitigation of transmit field inhomogeneity at high field greatly benefits from subject specific B1 mapping. However, the generally long scan times of mapping techniques limit their practical use. Here, modifications to the Bloch Siegert (BS) B1 mapping method are implemented to allow whole brain B1 mapping within 40s. The effectiveness of these modifications, including an improved gradient scheme, improved BS pulse, and EPI readout, is demonstrated in phantoms and human brain.

Keywords

abstract accuracy achieved acquisition addition allow alone amplitude applications applied automated available blocks blue brain calculating chemical coil coils common compute consistent constant containing control corporate corporation coverage crusher deposition development diagram direct directly distortion dummy effectiveness employed energy environment environments error errors example except excitation extremely fashion fold frequency gain gradient gradients green hampered health idea immediate implementation implemented important improved in vivo incorporated inhomogeneity initial institutes integrated interface isotropic kept lead least long magnet magnetization magnitude mapping maps masking matrix mediation medical minimize modified module multiplying national nominal normalization nova offsets optimized original oxford part particular peak performance peter phantom planned positive post potentially power practical processing proposed protocol pulse pulses quantify readout real reconstructed reconstruction reduce reducing reduction repetitions respectively response revisions sacrificing scaled scaling scanner scheme section sensitivity shape simulated simulation slice slices spoil submitted substantial term terms theory thereby threshold translated transmit unwrapping user validated variations volunteer whole