Meeting Banner
Abstract #0607

Adiabatic Pulse Design for Bloch-Siegert B1+ Mapping

Mohammad Mehdi Khalighi1, Brian K. Rutt2, Adam B. Kerr3

1Global Applied Science Lab, GE Healthcare, Menlo Park, CA, United States; 2Radiology Deaprtment, Stanford University, Stanford, CA, United States; 3Electrical Engineering Department, Stanford University, Stanford, CA, United States

B1+ mapping by the Bloch-Siegert (B-S) method has been shown to be fast and accurate; however, it suffers from high SAR and long TE. We have developed a new adiabatic B-S RF pulse design method, which achieves more B-S B1+ measurement sensitivity for a given pulse width, SAR and T2* than previous B-S pulse designs. A 2ms adiabatic B-S pulse generates 2.5 times more angle to noise ratio maps in the brain compared to 6ms conventional Fermi pulse with the same SAR. The adiabatic B-S pulse performance was validated both in phantoms and in vivo.

Keywords

accurate achieved address adequate adiabatic allows amplitude analytical applied assume assuming away band brain bring butt close closest comp comparing concept condition constant constraint cover create created creates deposition design designed designs differs effective electrical energy enough entire especially excitation former frame frequency fulfill generates gives global head hods inhomogeneity insensitive instance lead leads limit limits long magnetization magnitude mapping maps matrix maxim maximize maximizing measured metrically modified neck numerical offset optimized pared park phantom played problem profile programming property pulse pulses quality radiology repeated resonant respectively responses scanner science sensitivity serves short shorter slices smaller solution sought squared starting strongly subject suffers sulfate support theory thick tissue toward transverse utility varying volunteer water whole widths