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Abstract #0583

Improved Estimation of Cerebral Artery Branch Territories Using Cluster-Based Segmentation of Vessel-Encoded Pseudocontinuous ASL Data

SUMMA25Akash P. Kansagra1, Eric C. Wong2

1Radiology and Biomedical Imaging, UC San Francisco, San Francisco, CA, United States; 2Radiology and Psychiatry, UC San Diego, San Diego, CA, United States

Vessel encoded pseudo-continuous ASL allows non-invasive estimation of multiple cerebrovascular territories above the circle of Willis. Segmentation of vascular territories has traditionally been achieved by clustering of highly correlated tagging data. Here, we assess improvements in vascular territory estimation that occur when tagging efficiency data are supplemented with spatial data in the clustering scheme. These results offer a simple and straightforward means to enhance the accuracy of mapping of small cerebral artery branch territories.

Keywords

according accounting achieved acquisition acquisitions addition alone application approved arteries artery artifact assigned benefit biomedical bottom branch branches central cerebral channel circle classification cluster clustering clusters coil color colorization colorized combination combining complex compromised computed concordance concordant contained continuous coordinates corresponds created delay describe dimensional distinct distribution encoded encoding enhance enhanced estimation excitations existing expectation expected extending extent field five fraction generated geographic greater grossly half head healthy identification improved improvements included indicated indicating inflowing interleaves labeling larger length location made magnet manifest mapping maps maximization measured midpoint misclassification mixture model modifications normalized often overlap pairs patient perfusion permits plot populate positions post presence processed projection protocol pseudo psychiatry pulse quality radiology reasonable reduced reduces reliability repeated representative reproducibility resemble resolution respectively scatter segmentation shot similarity simple simultaneous space spatial speckling spiral step straightforward strategies subjects suggest supplemented tagging tags territories territory traditionally train vascular vessel view volunteers