Meeting Banner
Abstract #0562

MRI-Guided Cryoablation of Small Renal Tumors

R Jason Stafford1, Sanaz Javadi2, Elizabeth P. Ninan2, Yvette Teniente2, Li Pan3, Surena Matin4, Kamran Ahrar2

1Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; 2Interventional Radiology, The University of Texas MD Anderson Cancer Center; 3Center for Applied Medical Imaging, Siemens Corporate Research, Baltimore, MD; 4Urology, The University of Texas MD Anderson Cancer Center

Initial experience in clinical implementation of MRI guided cryotherapy on a 1.5T compact and wide bore system is presented. MRI is used for planning, targeting, monitoring and verification of delivery with long term patient follow-up in more than 15 patients. Initial results are summarized for treated patients as well as a description of the procedures and techniques used. We find that MRI guidance appears to provide similar outcomes as those observed in CT, but without additional radiation and a better ability to visualize the iceball in complex tissue environments during therapy delivery.

Keywords

ablation absent acceptable accommodate accomplished acquisition acquisitions adequately anatomy applied approaches artifacts assess background beat best beyond bore boundaries cancer carcinoma cell chosen clinical collected comparable compiled complications considered consisted consistent contained contrast correlation cross cycles cylindrical damage deficit deficits delivered delivery demographics demonstrating discovery dynamic early edges enhanced environments experience exquisite extended facilitated fatty feasibility feedback field fields formation free freeze gradient guidance guided haste initial integrates intermittent intervention invasive length lesion lesions location manipulate manipulation manipulations medical metal minutes modulated monitoring months needle oblique open option options orientation oriented outcomes pathology patient patients percutaneous perfusion physics placement planar planning post predicted preliminary presentation primarily primer probe problematic protocol radiation radiologist real recent reformatted relationship remaining renal report reported risen safely saturation soft steady substantially success successfully systems target targeted targeting technical technologist thawing therapy thereafter tissue treatment tumor tumors urology utilized verification verifying versus visualized wide widely years zone