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Abstract #0549

Diffusion Tensor Magnetic Resonance Tractography of the Prostate: Feasibility for Mapping Neurovascular Anatomy

Daniel Jason Aaron Margolis1, Benjamin Ellingson2, Shyam Natarajan3, Robert Reiter4, Taryar Zaw1, Peter Schulam4, Steven Raman1, David Finley5

1Department of Radiology, UCLA David Geffen School of Medicine, Los Angeles, CA, United States; 2Department of Radioloyg, UCLA David Geffen School of Medicine; 3Department of Bioengineering, UCLA David Geffen School of Medicine, Los Angeles, CA, United States; 4Department of Urology, UCLA David Geffen School of Medicine; 5Department of Urology, Kaiser Permanente Los Angeles

Eight men scheduled to prostatectomy underwent endorectal multiparametric magnetic resonance imaging (MRI) of the prostate with DTI. DTI tractography was successfully performed in all eight patients, visualizing fiber tracts around the prostate. DTI tractography of the prostate effectively visualized periprostatic fiber tract anatomy. Variation in tract distribution existed within individual patients and between patients. Some patients had disproportionately tract mass from one side of the prostate to the other. These findings have potential applicability for the generation of patient-specific pre-operative nerve sparing plans for RP and for the quantitative evaluation of potency outcomes.

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Keywords

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