Meeting Banner
Abstract #0520

High Spatio-Temporal Resolution Dixon Imaging Sequence for Multiphasic Contrast Enhanced Abdominal Imaging

Manojkumar Saranathan1, Dan Rettmann2, Brian A. Hargreaves1, Sharon Clarke1, Shreyas S. Vasanawala3

1Radiology, Stanford University, Stanford, CA , United States; 2Global Applied Science Laboratory, GE Healthcare, Rochester, MN, United States; 3Radiology, Stanford University, Stanford, CA, United States

High spatio-temporal resolution is essential in hepatobiliary imaging to characterize lesion morphology and to assess contrast uptake. In addition, late arterial phase imaging is critical for hypervascular tumors such as hepatocellular carcinoma (HCC) and neuroendocrine metastases. We demonstrate feasibility and clinical performance of a new high spatio-temporal resolution technique called DISCO (DIfferential Sub-sampling with Cartesian Ordering) that combines a dual-echo SPGR sequence with pseudo-random variable density k-space segmentation and a view sharing reconstruction. A high spatial resolution of 1.1x1.5x3 mm over 60 slices was routinely achieved with a temporal resolution of ~4 seconds, enabling clear delineation of angiographic, hepatic arterial, hepatic venous and portal venous phases.

Abstract PDF Presentation Video

Keywords

abdominal acceleration achieved addition adjacent agent applied array arrow arrows arterial arteries artifacts background bandwidth black blue breath briefly calibration capture captured carcinoma central channel clear clearance clinical coherent coil comparable comparing compressed confined consecutive consensus contrast critical dashed delineation density depicted disco dose dual dynamic effectively elements enabling enhanced enhancement enhancing example fast feasibility female flex fully future gadolinium green grid hepatic hold hyper identified illustrated includes incorporated injection innermost intensity laboratory late lava lesions linear liver long male matrix minimizing motion much note observable optimized optimizing outer overall parallel particularly patient patients portal post preliminary progressive progressively pseudo quality radiology radius random rapid rapidly reaching readout reconstruction recorded representative resolution review routinely sampled sampling scale scheme schemes segmentation severity sharing slices solid space spatial successive suppression temporal thick thin timing torso trajectory transient tumor tumors upper uptake variable vascular vein veins venous view visualized wash washed washout white year