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Abstract #0439

Time-Resolved Phosphorous Magnetization Transfer of the Human Calf Muscle at 3T & 7T: A Feasibility Study

MAGNA25Ladislav Valkovic1, 2, Marek Chmelik1, Ivica Just Kukurova1, Martin Krk3, Stephan Gruber1, Ivan Frollo4, Siegfried Trattnig1, Wolfgang Bogner1

1MR Centre of Excellence, Department of Radiology, Medical University of Vienna, Vienna, Austria; 2Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences , Bratislava, Slovakia; 3Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; 4Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia

The aim of this study was to compare precision of magnetization transfer (MT) experiments at 3T&7T and to analyze the potential time resolution of MT at 7T. Calf muscles of six healthy subjects were consecutively measured on two MR scanners (3T&7T). The MT protocol was split to four parts (each 10min 36sec) to compare the variability of repeated measurements and to test time resolved MT experiments. No MT experiments of the skeletal muscle have been performed as yet at 7T. We were able to show that the time-resolved MT in the muscle with ~10min temporal resolution is feasible at 7T.

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