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Abstract #0347

Applications Now & in the Future, Across a Range of Areas (Disease & Biology)

Jeffrey Joseph Neil1

1Washington University School of Medicine, St. Louis, MO, United States

We will review the application of T2*- and diffusion-based assessments of tissue microstructure in bone, lung, heart, tumor, and developing brain. Both basic science and clinical applications will be discussed, including osteoporosis, emphysema, myocardial injury, tumor response to therapy, and differential rates of cortical development.

Keywords

adaptable addition address adult aging airways altered alveolar alveoli animals anisotropy application applications applied approachable approaches array assessed available basic beating better biological bone brain brains cancers caused cell challenging clinical clinically complementary consists contexts converse correlations cortex covered crossing cylindrical density depth destroyed detect detectable determine developing development diagnostic differential difficult diffusion disease disorder duct earlier early elderly emphysema evaluating example failure fall favorable fracture fractures function gradually health heart helical human hypothesized identifying in vivo indicator infants inhaled involves layers lumen lung major marrow measures measuring mice modalities modeled motor moving myocardial myocardium network nevertheless organization osteoporosis outcome particularly pathological patients place premature presentation pretreatment problem prognostic progresses prolongs pulmonary questions radii readily reduction remains representative response review school sensitivity sleeve smokers spacing species specimens spine stages status strategies structural structure susceptibility take technically therapeutic therapy though tissue tissues treatment true tumor tumors typically underlying variety volume whereas white wrist yields