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Abstract #0330

SE FMRI in Human Bilateral Auditory Cortex Using B1 Shimming

Federico De Martino1, 2, Sebastian Schmitter1, Kamil Ugurbil1, Elia Formisano2, Essa Yacoub1, Pierre-Francois van de Moortele1

1Radiology, Center for Magnetic Resonance Research, Minneapolis, MN, United States; 2Cognitive Neuroscience, Maastricht University, Maastricht, Netherlands

We aim at using SE-fMRI to push further the investigation of functional organization in the human auditory cortex. To do so we investigate the use of an RF coil that includes 8 Transceivers (8TCx), allowing for the use of B1 shimming over right and left auditory cortices, as well as 24 Receive only channels (24Rx), providing higher SNR. We demonstrate successful SE-fMRI in bilateral auditory cortex at 7T highlighting significant differences between responses to voice vs. non-voice stimuli in anterior areas of the superior temporal sulcus and gyrus.

Keywords

accordingly achieve achieved acquisition allowing allows amplitude analyses animals anterior around auditory axial bilateral blocks bold brain calibrated carried categories channel channels clear close cognitive coil coils columnar columns conjunction consisted conspicuous contrast correction cortex cortices crossing deliberately destructive detecting detection draining efficiency exceeding excitation expected field foundation functional funded gaps gradient hand head healthy highlight homogeneous human initial interferences investigate investigation lateral latter like limits linear lobe long manually maps material millimeter minutes mode model modulated motion motivation natural nature neuron noise normalized oblique optimized orientation originating part power powered preliminary preserve previously prior processing providing pulses purchase quadrature radiology reach reasonably receive reducing reduction refocusing regime relies resolution responses robust scale sensitivity settings shimming short slice slices smoothing solution sounds spatial specificity speech spin stimuli strongly structure subject substantial successful sufficiently superior supporting surface target tones tools topographical transceivers transmit transversal typically ultra veins views visual voice voices whereas