Meeting Banner
Abstract #0321

Dual Imaging with Bright Blood Arterial Input Function & Black Blood Tissue Acquisition for Vessel Wall Imaging in Atherosclerosis: BB-SHILO (Black-Blood Simultaneous High-Low Temporal (Low-High Spatial) Resolution Imaging)

Philip M. Robson1, Claudia Calcagno1, Sarayu Ramachandran1, Venkatesh Mani1, Melanie Kotys-Traughber2, Zahi A. Fayad1

1Translational and Molecular Imaging Institute, Mount Sinai School of Medicine, New York, NY, United States; 2Philips Healthcare, Cleveland, OH, United States

A new sequence interleaving bright-blood GRE full-image and dark-blood SE image-segment acquisitions is investigated for application to quantitative Dynamic Contrast Enhanced imaging of the carotid arteries in atherosclerosis. Bright-blood images are acquired with 1-sec temporal and low 0.5x4-mm spatial resolutions to capture the arterial input function, while the interleaved dark-blood images have lower temporal and 0.5x0.5-mm spatial resolution to image the thin vessel wall without blooming of the bright vessel lumen. This study in three subjects demonstrates the feasibility of simultaneously-acquired combined image contrasts. Contrast agent kinetic parameters measured in the vessel wall are consistent with those in the literature.

Abstract PDF Presentation Video

Keywords

acceleration accurately acknowledged acquisition acquisitions addition addressed administration around arterial arteries artery assess assessment assumed atherosclerosis bifurcation black blood bolus bright carotid caudally centric clinical common comprising concentration consent consistent contrast curves dark demonstrating desirable detail diagram dose dual dubbed effective either eliminate employed establish every except excitation extract feasibility features flushed frame frames free full function gained gatehouse giving good gradient implement independence inflowing informed injected injection input insert institute investigate kinetic latter length linear literature lumen matrix measured methodology minutes model molecular mount moved obscuring optimal parker partial perpendicular perturbation pixel placed plaques played prepared prevent prior proposed pulse quality recently relationship reordering repetition reported required requires resolution sampling saturate saturation school segment segmented selective sense separate separately shape shot simultaneous simultaneously slice slices slower spanning spatial spin steady strategy subject subjects suppressed suppression system table taking target temporal thin tissue translational typical uptake variation vessel wall widely written