Meeting Banner
Abstract #0318

i-T2Prep: Flow-Independent 3D Whole Heart Vessel Wall Imaging Using an Interleaved T2-Preparation Acquisition

MAGNA25Marcelo E. Andia1, Markus Henningsson1, Tarique Hussain1, Alkystis Phinikaridou1, Gerald Greil1, Rene M. Botnar1

1Division of Imaging Sciences and Biomedical Engineering, Kings College London, London, United Kingdom

We present a novel technique for flow-independent vessel wall imaging based on the differences in T2-relaxation time of arterial blood and surrounding tissues using a T2prep prepulse. The technique is based on the acquisition and subtraction of two datasets, one obtained with and one without T2prep. The subtraction step allows nulling the signal of arterial blood while maintaining signal of muscle and vessel wall. In order to minimize the motion sensitivity we developed an interleaved acquisition for the T2prep and non-T2prep images, which allows obtaining coronary vessel wall images from a whole heart acquisition with minimal misregistration artefacts.

Keywords

acquisition additional address advantage advantages allows angina angiography another aorta applied arterial arteries artery assessment atherosclerosis attenuation attractive beat best better biomedical black blood bright carotid challenges channel characteristic circulation clinical coil college combined completely computed contrast coronaries coronary coverage culprit decay decays demonstrating developed direct directly disease division double duration durations easy engineering equipped even events every expected extensive faster feasibility findings flow future great guide healthy heart help identify implement implemented independent insensitivity interleaved invasive inversion kingdom kings lesion limitation limited long longer longitudinal magnetization magnitude maintained maintaining making medical minimize minimizing muscle myocardium novel null nulling outward patients plaque potential prep preparation problem propose protocol rapid rapidly reached receiver recent recovery reformatted rely representative risk scanner sciences sets shorter simulation slice slowly spatial stable studies subjects subtracted subtraction successfully suggest surrounding takes targeted therapy thoracic tissues tomography translation ultrasound underlying validated vessel visualization visualize wall whole