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Abstract #0253

Quantitative Improvement in FA Values in Various Fiber Bundles Is Associated with Improvement in Clinical Grade of Children with Cerebral Palsy Following Therapy

Saurabh Chaturvedi1, Puneet Goyal2, Vimal K. Paliwal3, Ankita Chourasia1, Yogita Rai1, Ravindra Kumar Garg4, Ram Kishore Singh Rathore5, Rakesh Kumar Gupta1

1Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar pradesh, India; 2Anaesthesiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; 3Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, UP, India; 4Neurology, Chhatrapati Sahu ji Maharaj Medical University, Lucknow, Uttar Pradesh, India; 5Indian Institute of Technology, Kanpur

We examined 10 CP children twice (10 base line&10 follow up at 6month; 8 boys&2 girls) (mean age=6 years) who had spastic diplegia, GMFM score ranging from 50-60 and with grade II spasticity. There was a significant difference between FA values of baseline and follow-up in left motor, left sensory, CG, ATR, PTR bundles. A significant positive correlation was found between GMFM scores and FA values of left motor (r=0.723, p<0.001), left sensory (r=0.609, p=0.004), CG (r=0.787, p<0.001) and ATR (r=0.420, p=0.065).We conclude that improvement in white matter fibers is associated with physical improvement in these children.

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Keywords

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