Meeting Banner
Abstract #0230

Myocardial Velocity & T2 Mapping Reveals Changes in LV Structure & Function After Heart Transplantation

MAGNA25Rahul Rustogi1, Mauricio Galizia1, Jeremy Collins1, Darshit Thakrar1, Asad Usman1, Bernd Jung2, Daniela Foell3, Saurabh Shah4, James Carr1, Michael Markl1

1Radiology and Biomedical Engineering, Northwestern University Feinberg School of Medicine, Chicago, IL, United States; 2Medical Physics, Freiburg University Medical Center, Freiburg, Germany; 3Cardiology, Freiburg University Medical Center, Freiburg, Germany; 4Siemens Healthcare, Chicago, United States

In a pilot study using a small cohort of post cardiac transplantation patients, we demonstrate the ability of novel non-invasive myocardial velocity mapping and T2 mapping to reveal underlying changes in myocardial structure and function. T2 maps assess myocardial edema while myocardial velocity maps detect changes in diastolic relaxation. Post transplant patients showed significant heterogeneity in distribution of T2 relaxation times and reduced peak radial and long axis velocities compared with normal control subjects. Very good agreement was found between independent readers indicating myocardial velocity mapping to be a highly reproducible method for assessing diastolic dysfunction.

Abstract PDF Presentation Video

Keywords

academic acceleration acquisition acute advanced agreement allowing assess assessment association asymptomatic automated axis background basal biomedical biopsy black bland blood borders breath card cardiac cardiology cardiovascular cellular clinical cohort cohorts color components control controls detecting diastolic direct directional disordered distribution drawing edema eliminate encoding engineering evaluate even exam examined excellence female function functional gated gender good grade heart heterogeneous include included independent indicating individual integrated inter invasive limitations limits long manual manually mapping matched medical medicine minor model monitoring months motion myocardial myocardium observer observers offsets parallel past patient patients peak physics pixel poorly post prepared previous previously prior problematic propose proposed proven quantitative radial radiology readers reduced reflected regional registered rejection remote representing reproducible resolution resolved reveals school segment segmental segments shah short sided slice spatially structural structure subject substantial subtle suppl support symptoms systolic temporal transformation transplant transplantation underlying utilized variability variable variation velocities velocity ventricle ventricular wise years